Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935572 | 0.83 | PPARA (0.54) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL3935560 | 0.83 | PPARA (0.54) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL31407563 | 0.82 | PPARA (0.53) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL625897 | 0.77 | PPARA (0.48) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL625898 | 0.77 | PPARA (0.48) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL28009771 | 0.75 | ALDH1A1 (0.44) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL28009772 | 0.75 | ALDH1A1 (0.44) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL29866102 | 0.75 | PPARA (0.57) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL26932496 | 0.75 | PPARA (0.57) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL556571 | 0.75 | PPARA (0.57) | PPARAPPARGACEPPARDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244616-A1 | (HETERO)BICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SmithKline Beecham plc (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047874-A1 | (HETERO)BICYCLYMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-07-05 | — | — | WO | disclosed |