Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 15/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481782 | 0.87 | MEN1 (0.42) | MBOAT4 | |
| SCHEMBL1172890 | 0.78 | KMT2A (0.42) | TSHR | |
| SCHEMBL16139727 | 0.77 | MYC (0.54) | TSHR | |
| SCHEMBL20441084 | 0.76 | MAPT (0.42) | TSHR | |
| SCHEMBL28604131 | 0.70 | LRRK2 (0.36) | TRPV4TSHR | |
| SCHEMBL3501215 | 0.68 | TRPV4 (0.32) | TRPV4TSHRUPP1 | |
| SCHEMBL4261991 | 0.68 | TRPV4 (0.32) | TRPV4TSHRUPP1 | |
| SCHEMBL28597079 | 0.65 | KDM4E (0.43) | TRPV4TSHRUPP1 | |
| SCHEMBL30352797 | 0.65 | KDM4E (0.43) | TRPV4TSHRUPP1 | |
| SCHEMBL152358 | 0.61 | TSHR (0.39) | TRPV4TSHRUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002007780-A2 | METHODS FOR IDENTIFYING THERAPEUTIC TARGETS | NEWBIOTICS, INC. (US) | 2002-01-31 | — | — | WO | disclosed |