Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472656 | 0.87 | USP2 (0.33) | USP2GAAHSD17B10 | |
| SCHEMBL7470575 | 0.86 | USP2 (0.45) | USP2KMT2AMEN1GAAMAPT | |
| SCHEMBL7463447 | 0.85 | HSD17B10 (0.41) | USP2GAATP53SMN1; SMN2HSD17B10 | |
| SCHEMBL7475251 | 0.84 | HSD17B10 (0.40) | USP2KMT2AMEN1GAAMAPT | |
| SCHEMBL7473265 | 0.82 | KMT2A (0.38) | USP2KMT2AMEN1GAAMAPT | |
| SCHEMBL7472405 | 0.82 | PARP1 (0.45) | KMT2AMEN1GAAMAPTTP53 | |
| SCHEMBL7472179 | 0.82 | KMT2A (0.38) | USP2KMT2AMEN1GAAMAPT | |
| SCHEMBL7468474 | 0.81 | BRD4 (0.35) | — | |
| SCHEMBL7476297 | 0.81 | ALOX5 (0.42) | USP2KMT2AMEN1GAAMAPT | |
| SCHEMBL7468810 | 0.80 | BRD4 (0.38) | USP2KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |