Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472662 | 0.86 | L3MBTL1 (0.43) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL7470585 | 0.85 | USP2 (0.56) | L3MBTL1USP2GAAHSD17B10MAPT | |
| SCHEMBL7463453 | 0.84 | HSD17B10 (0.48) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL5802317 | 0.84 | L3MBTL1 (0.43) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL7475254 | 0.83 | HSD17B10 (0.46) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL19023500 | 0.81 | USP2 (0.44) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL7473268 | 0.81 | L3MBTL1 (0.41) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL7472416 | 0.81 | PARP1 (0.48) | MAPK1USP2GAAHSD17B10MAPT | |
| SCHEMBL190342 | 0.81 | KMT2A (0.51) | L3MBTL1MAPK1USP2GAAHSD17B10 | |
| SCHEMBL7469309 | 0.80 | L3MBTL1 (0.59) | L3MBTL1MAPK1USP2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |