Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 6/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.51 |
| ▸ | GSK3B | P49841 | 4/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | NEK4 | P51957 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464448 | 1.00 | CISD1 (0.51) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL14492593 | 0.92 | RXRA (0.59) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL5492185 | 0.92 | RXRA (0.59) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL5492186 | 0.92 | RXRA (0.59) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL7458010 | 0.92 | PIM1 (0.52) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL7458015 | 0.92 | PIM1 (0.52) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL5487591 | 0.90 | PIM1 (0.52) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL14492757 | 0.90 | PIM1 (0.52) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL5487590 | 0.90 | PIM1 (0.52) | CISD1PIM1PIM2GSK3BPIM3 | |
| SCHEMBL7462891 | 0.88 | PIM1 (0.48) | CISD1PIM1PIM2GSK3BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |