Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.54 |
| ▸ | ITGAV | P06756 | 7/20 | 0.54 |
| ▸ | CASR | P41180 | 8/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551456 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BITGAVCASRMEN1 | |
| SCHEMBL382764 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BITGAVCASRMEN1 | |
| SCHEMBL7461042 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGAVCASR | |
| SCHEMBL7464434 | 0.84 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL7052283 | 0.84 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL7466752 | 0.81 | ITGB3 (0.72) | ITGB3ITGA2BITGAV | |
| SCHEMBL6499964 | 0.81 | KAT6A (0.43) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL7654428 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BITGAVKDM4EMAPT | |
| SCHEMBL7461679 | 0.80 | ITGB3 (0.38) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL382782 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |