Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696313 | 0.87 | TSHR (0.50) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL468366 | 0.83 | ALDH1A1 (0.36) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9646819 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1CYP1A2ALOX15 | |
| Potassium SCHEMBL8421932 | 0.79 | ALDH1A1 (0.33) | TSHRALDH1A1ALOX15 | |
| SCHEMBL9647771 | 0.79 | ALDH1A1 (0.33) | TSHRALDH1A1ALOX15 | |
| Pentachlorophenol SCHEMBL23121452 | 0.79 | HSD17B10 (1.00) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL1330735 | 0.79 | HSD17B10 (1.00) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL1492 | 0.79 | HSD17B10 (1.00) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL5315995 | 0.79 | HSD17B10 (1.00) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| Pentachlorophenol SCHEMBL21647360 | 0.75 | HSD17B10 (0.91) | TSHRHPGDHSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098880-A4 | DECHLORINATION OF PYRIDINES IN ACIDIC, ZINC-CONTAINING MEDIUMS | REILLY IND INC (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-1098880-A1 | DECHLORINATION OF PYRIDINES IN ACIDIC, ZINC-CONTAINING MEDIUMS | REILLY INDUSTRIES, INC. (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6184384-B1 | PREPARING 3,5-DICHLOROPYRIDINES BY DECHLORINATING HIGHER-CHLORINATED PYRIDINE COMPOUNDS SUCH AS 2,3,5,6-TETRACHLOROPYRIDINE IN AN ACIDIC MEDIUM IN THE PRESENCE OF ZINC AND OPTIONALLY A QUATERNARY AMMONIUM | REILLY INDUSTRIES, INC. | 2001-02-06 | — | — | US | disclosed |
| WO-2000003989-A1 | DECHLORINATION OF PYRIDINES IN ACIDIC, ZINC-CONTAINING MEDIUMS | REILLY INDUSTRIES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |