SCHEMBL7464742

SCHEMBL7464742

NC(=O)/C(=N\OCF)c1nsc(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7464751 1.00
Hydrochloric Acid SCHEMBL5995504 0.90
Hydrochloric Acid SCHEMBL7469956 0.90
SCHEMBL8763397 0.90
SCHEMBL7470099 0.90
SCHEMBL7470094 0.90
SCHEMBL9199421 0.88
Hydrochloric Acid SCHEMBL7469951 0.88
SCHEMBL5099297 0.88
SCHEMBL9199416 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066812-A Chemical intermediates for bactericides EISAI CO., LTD. (JP) 1991-11-19 US claimed
CN-1142937-C Antibacterial cephalosporins �Ҵ���˾ 2004-03-24 CN disclosed
EP-0764648-B1 Cephem derivatives and process for the preparation thereof EISAI CO LTD (JP) 2002-01-16 EP disclosed
CN-1186494-A Antibacterial cephalosporins BIOCHEMIE GMBH (AT) 1998-07-01 CN disclosed
EP-0333154-B1 Process for the preparation of cephem derivatives EISAI CO LTD (JP) 1997-07-16 EP disclosed
EP-0764648-A1 Cephem derivatives and process for the preparation thereof Eisai Co., Ltd. (JP) 1997-03-26 EP disclosed
EP-0612751-A2 Compounds for the preparation of cephem derivatives Eisai Co., Ltd. (JP) 1994-08-31 EP disclosed
US-5128465-A Containing thiadiazole ring and fluorine substitution EISAI CO., LTD. (JP) 1992-07-07 US disclosed
EP-0264091-B1 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE Eisai Co., Ltd. (JP) 1992-02-05 EP disclosed
US-5066812-A Chemical intermediates for bactericides EISAI CO., LTD. (JP) 1991-11-19 US disclosed
US-5006649-A Bactericides EISAI, CO. (JP) 1991-04-09 US disclosed
US-4921850-A GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE EISAI CO., LTD. (JP) 1990-05-01 US disclosed
EP-0333154-A2 Process for the preparation of cephem derivatives and intermediates therefor Eisai Co., Ltd. (JP) 1989-09-20 EP disclosed
EP-0264091-A2 3-Propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1988-04-20 EP disclosed