⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763397 | 1.00 | — | — | |
| SCHEMBL7470099 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5995504 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7469956 | 1.00 | — | — | |
| Water SCHEMBL9142929 | 0.99 | — | — | |
| Water SCHEMBL9142933 | 0.99 | — | — | |
| SCHEMBL7464742 | 0.90 | — | — | |
| SCHEMBL7464751 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL8176562 | 0.89 | — | — | |
| SCHEMBL9687250 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066812-A | Chemical intermediates for bactericides | EISAI CO., LTD. (JP) | 1991-11-19 | — | — | US | claimed |
| JP-4128277-A | — | — | None | — | — | JP | disclosed |
| EP-0764648-B1 | Cephem derivatives and process for the preparation thereof | EISAI CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0333154-B1 | Process for the preparation of cephem derivatives | EISAI CO LTD (JP) | 1997-07-16 | — | — | EP | disclosed |
| EP-0590681-B1 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI KAGAKU KK (JP) | 1997-07-09 | — | — | EP | disclosed |
| EP-0764648-A1 | Cephem derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |
| US-5428173-A | Halogenating corresponding aminothiadiazolylacetic acid | EISAI CHEMICAL CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0287116-B1 | Thiadiazolylacetamide cephem derivatives | EISAI CO LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0612751-A2 | Compounds for the preparation of cephem derivatives | Eisai Co., Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0590681-A2 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI CHEMICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5089491-A | Active against both gram-negative and gram-positive bacteria | EISAI CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0264091-B1 | 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5066812-A | Chemical intermediates for bactericides | EISAI CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| US-5006649-A | Bactericides | EISAI, CO. (JP) | 1991-04-09 | — | — | US | disclosed |
| US-4929612-A | ANTIBIOTICS, BACTERICIDES | EISAI CO., LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| US-4921850-A | GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE | EISAI CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| CN-1036769-A | The method for preparing Cephem Derivative and intermediate thereof | EISAI CO LTD (JP) | 1989-11-01 | — | — | CN | disclosed |
| EP-0333154-A2 | Process for the preparation of cephem derivatives and intermediates therefor | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |
| EP-0287116-A2 | Thiadiazolylacetamide cephem derivatives | Eisai Co., Ltd. (JP) | 1988-10-19 | — | — | EP | disclosed |
| EP-0264091-A2 | 3-Propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |