Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.85 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463672 | 0.92 | CMA1 (1.00) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL7466207 | 0.87 | CMA1 (0.85) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL7465666 | 0.87 | CMA1 (0.85) | CMA1CA9CA12LMNACA1 | |
| SCHEMBL3788201 | 0.87 | CMA1 (0.85) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL3775614 | 0.87 | CMA1 (0.85) | CMA1CA9CA12MEN1KMT2A | |
| SCHEMBL3781496 | 0.86 | CMA1 (0.71) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL3782209 | 0.86 | CMA1 (0.71) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL7461590 | 0.86 | CMA1 (0.79) | CMA1CA9CA12FEN1LMNA | |
| SCHEMBL7460037 | 0.86 | CMA1 (0.67) | CMA1CA9CA12FEN1CA1 | |
| SCHEMBL7464440 | 0.85 | CMA1 (0.77) | CMA1CA9CA12FEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |