Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.85 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463672 | 0.92 | CMA1 (1.00) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7461914 | 0.88 | CMA1 (0.77) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL3788201 | 0.87 | CMA1 (0.85) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL3775614 | 0.87 | CMA1 (0.85) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7466207 | 0.87 | CMA1 (0.85) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7464965 | 0.87 | CMA1 (0.85) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7467052 | 0.86 | CMA1 (0.79) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7468062 | 0.85 | CMA1 (0.77) | CMA1CA9CA12HAVCR2CA1 | |
| SCHEMBL7460816 | 0.85 | CMA1 (0.68) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3785292 | 0.84 | CMA1 (0.72) | CMA1CA9CA12HAVCR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |