Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3875666 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL3875669 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL2224538 | 0.82 | ALDH1A1 (0.55) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL15401707 | 0.76 | PARP1 (0.49) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL15401706 | 0.76 | PARP1 (0.49) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL27660527 | 0.75 | ALDH1A1 (0.55) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL10622090 | 0.75 | ALDH1A1 (0.55) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4573034 | 0.75 | ALDH1A1 (0.55) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4573806 | 0.73 | ALDH1A1 (0.53) | ALDH1A1ADAMTS5KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28479905 | 0.71 | MAPT (0.50) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |