SCHEMBL7465006

SCHEMBL7465006

CC=Cc1cc(C(F)C(F)(F)C(F)(F)F)ccc1OS(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.41
MAPT P10636 9/20 0.36
LMNA P02545 6/20 0.36
GAA P10253 4/20 0.36
TDP1 Q9NUW8 3/20 0.36
KMT2A Q03164 6/20 0.36
MEN1 O00255 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 2/20 0.34
MAPK1 P28482 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALPL P05186 1/20 0.33
HTT P42858 3/20 0.32
PKM P14618 2/20 0.32
KDM4E B2RXH2 4/20 0.32
EYA2 O00167 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466063 0.86 CXCR2 (0.33)
SCHEMBL8501653 0.86 MEN1 (0.37) GAAKMT2AMEN1
SCHEMBL7454336 0.82 MAPT (0.42) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL8499836 0.81 ALDH1A1 (0.47) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL8525955 0.80 ALDH1A1 (0.46) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL7465001 0.80 ALDH1A1 (0.41) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL7473637 0.80 ALDH1A1 (0.41) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL7465008 0.80 ALDH1A1 (0.41) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL3845302 0.79 ALDH1A1 (0.48) ALDH1A1MAPTLMNAGAATDP1
SCHEMBL3845304 0.79 ALDH1A1 (0.48) ALDH1A1MAPTLMNAGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020172652-A1 Composition for film formation and material for insulating film formation JSR CORPORATION (JP) 2002-11-21 US disclosed
EP-1245638-A1 Composition for insulating film formation JSR Corporation (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020172652-A1 Composition for film formation and material for insulating film formation VCL, BMI1, PUF60 ALDH1A1 2731/4885MAPT 649/4885LMNA 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.