Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332511 | 0.71 | HPGD (0.53) | MAOASIGMAR1NAAAMAPTRXFP1 | |
| SCHEMBL27372800 | 0.70 | HTR2C (0.49) | HTR2C | |
| SCHEMBL1226782 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL6546948 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL8096690 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL2823250 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL8095284 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL676854 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL1433686 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL8094527 | 0.70 | SIGMAR1 (0.71) | MAOASIGMAR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817773-B1 | PYRIMIDINE COMPOUNDS | QINETIQ LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| US-6121448-A | LIQUID CRYSTALLINE COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITTANIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-09-19 | — | — | US | disclosed |
| US-5986096-A | REACTION OF HYDROGEN IODIDE WITH CHLORO-5-BROMOPYRIMIDINE | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S A GOVERNMENT OF THE U.K. OF GT. BRITAIN & N. IRELAND OF DEFENCE EVALUATION & RESEARCH AGENCY (GB) | 1999-11-16 | — | — | US | disclosed |
| WO-1996030344-A2 | PYRIMIDINE COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1996-10-03 | — | — | WO | disclosed |