Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 12/20 | 0.44 |
| ▸ | ESR1 | P03372 | 12/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7467778 | 0.88 | HRAS (0.49) | HRASESR1ESR2EGFRERBB2 | |
| SCHEMBL7467474 | 0.83 | HRAS (0.47) | HRASESR1ESR2BRD4EGFR | |
| Hydrochloric Acid SCHEMBL7465253 | 0.81 | HRAS (0.52) | HRASESR1ESR2EGFRERBB2 | |
| SCHEMBL7472023 | 0.80 | HRAS (0.51) | HRASESR1ESR2EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7475008 | 0.78 | HRAS (0.64) | HRASESR1ESR2EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7471999 | 0.77 | HRAS (0.52) | HRASESR1ESR2EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7465588 | 0.77 | HRAS (0.46) | HRASESR1ESR2EGFR | |
| Hydrochloric Acid SCHEMBL7466261 | 0.76 | HRAS (0.49) | HRASESR1ESR2EGFRERBB2 | |
| SCHEMBL7467693 | 0.76 | HRAS (0.47) | HRASESR1ESR2HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL7465502 | 0.75 | HRAS (0.58) | HRASESR1ESR2EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |