Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 12/20 | 0.47 |
| ▸ | ESR1 | P03372 | 12/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467520 | 0.88 | MAPT (0.47) | CFTRMLLT1BRD4BCHEMAPT | |
| SCHEMBL7472023 | 0.88 | HRAS (0.51) | HRASESR1ESR2EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7471999 | 0.88 | HRAS (0.52) | HRASESR1ESR2CFTREGFR | |
| Hydrochloric Acid SCHEMBL7475008 | 0.85 | HRAS (0.64) | HRASESR1ESR2EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7466261 | 0.84 | HRAS (0.49) | HRASESR1ESR2EGFRERBB2 | |
| SCHEMBL7465223 | 0.83 | HRAS (0.44) | HRASESR1ESR2MLLT1EGFR | |
| Hydrochloric Acid SCHEMBL7477283 | 0.82 | HRAS (0.50) | HRASESR1ESR2EGFRERBB2 | |
| SCHEMBL7470540 | 0.81 | MEN1 (0.45) | HRASESR1ESR2MAPT | |
| Hydrochloric Acid SCHEMBL7468841 | 0.80 | MEN1 (0.44) | HRASESR1ESR2MAPT | |
| SCHEMBL7469237 | 0.80 | HRAS (0.45) | HRASESR1ESR2EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |