Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434292 | 0.93 | NR4A1 (0.61) | NR4A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30791463 | 0.87 | CDC25B (0.69) | MAPK13MAPK12MAPK11MAPK14CDC25B | |
| SCHEMBL23758169 | 0.87 | SLC6A4 (0.56) | NR4A1SLC6A4SLC6A3ALDH1A1CES2 | |
| SCHEMBL472751 | 0.87 | ALDH1A1 (0.63) | MAPK13MAPK12MAPK11MAPK14CDC25B | |
| SCHEMBL10631889 | 0.85 | SLC6A4 (0.66) | NR4A1SLC6A4SLC6A3BCAT2CYP1A2 | |
| Benzophenone SCHEMBL27513399 | 0.85 | ALDH1A1 (0.61) | MAPK13MAPK12MAPK11MAPK14CDC25B | |
| SCHEMBL7167629 | 0.84 | LIG1 (0.61) | MAPK13MAPK12MAPK11MAPK14CDC25B | |
| SCHEMBL26803787 | 0.84 | NR4A1 (0.53) | NR4A1SLC6A4SLC6A3ATMALDH1A1 | |
| Ethyne SCHEMBL14893380 | 0.83 | ALDH1A1 (0.59) | MAPK13MAPK12MAPK11MAPK14CDC25B | |
| SCHEMBL28426531 | 0.83 | ATM (0.58) | NR4A1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948343-B | Polymer containing sulfoxide group and preparation method thereof | 吉林大学 | 2020-03-10 | — | — | CN | claimed |
| CN-109081920-B | Prepolymer containing sulfoxide structure, preparation method thereof and advanced composite material | 吉林大学 | 2019-12-06 | — | — | CN | claimed |
| CN-108948343-B | Polymer containing sulfoxide group and preparation method thereof | 吉林大学 | 2020-03-10 | — | — | CN | disclosed |
| CN-109081920-B | Prepolymer containing sulfoxide structure, preparation method thereof and advanced composite material | 吉林大学 | 2019-12-06 | — | — | CN | disclosed |
| EP-1058678-B1 | METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES | MASSACHUSETTS INST TECHNOLOGY (US) | 2002-12-11 | — | — | EP | disclosed |