⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701871 | 0.80 | — | — | |
| SCHEMBL142284 | 0.71 | — | — | |
| SCHEMBL9644026 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL1592697 | 0.66 | — | — | |
| Methoxymethane SCHEMBL8952224 | 0.64 | — | — | |
| SCHEMBL2402570 | 0.62 | TSHR (0.59) | — | |
| SCHEMBL2402573 | 0.62 | TSHR (0.59) | — | |
| SCHEMBL11027057 | 0.62 | — | — | |
| SCHEMBL17706768 | 0.62 | TSHR (0.59) | — | |
| SCHEMBL2450670 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | claimed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | claimed |
| EP-3150581-A1 | PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2017-04-05 | — | — | EP | claimed |
| EP-2091926-B1 | SUBSTITUTED PYRAZOLE AND TRIAZOLE COMPOUNDS AS KSP INHIBITORS | NOVARTIS AG (CH) | 2015-10-21 | — | — | EP | claimed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | claimed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | claimed |
| EP-1765789-B1 | N-(1-(1-BENZYL-4-PHENYL-1H-IMIDAZOL-2-YL)-2,2-DIMETHYLPROPYL)BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS KINESIN SPINDLE PROTEIN (KSP) INHIBITORS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2013-02-27 | — | — | EP | claimed |
| US-20130017196-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVES | CHIRON CORPORATION | 2013-01-17 | — | — | US | claimed |
| US-8318791-B2 | Substituted imidazole derivatives | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2012-11-27 | — | — | US | claimed |
| US-4952577-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-08-28 | — | — | US | claimed |
| EP-0199446-B1 | PENEM COMPOUNDS, PRODUCTION AND USE THEREOF | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1990-06-13 | — | — | EP | claimed |
| EP-0359536-A2 | Cephalosporin compounds, process for their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1990-03-21 | — | — | EP | claimed |
| WO-1989004821-A1 | N-(BIPHENYLMETHYL)-3-HYDROXYGLUTARAMIC ACID AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1989-06-01 | — | — | WO | claimed |
| EP-0295100-A1 | Methoxymethyl compounds | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-12-14 | — | — | EP | claimed |
| US-4725581-A | NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS | ADIR ET COMPAGNIE (FR) | 1988-02-16 | — | — | US | claimed |
| EP-0252885-A1 | Bicyclic thiaaza compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |
| EP-0199446-A1 | Penem compounds, production and use thereof | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1986-10-29 | — | — | EP | claimed |
| US-4496484-A | Penicillin derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | claimed |
| EP-0078668-A1 | Preparation of aminocyclopentanealkenoic acids | GLAXO GROUP LIMITED (GB) | 1983-05-11 | — | — | EP | claimed |