SCHEMBL142284

SCHEMBL142284

O=C1CCC=CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL8952224 0.91
SCHEMBL28933278 0.89
SCHEMBL28850383 0.89 ALDH1A1 (0.33)
SCHEMBL2450670 0.84
SCHEMBL8445315 0.80 CA1 (0.36)
Methane SCHEMBL15227989 0.74
SCHEMBL14122224 0.74
SCHEMBL17706768 0.71 TSHR (0.59)
SCHEMBL19873 0.71
SCHEMBL2402570 0.71 TSHR (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2216 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250221944-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBLUEBIO INC (KR) 2025-07-10 US claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
EP-4506328-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBlueBio Inc (KR) 2025-02-12 EP claimed
CN-117986219-A Method for preparing thioglycoside from 6-aryl/alkylthio-2H-pyran-3-ketone compound 三峡大学 2024-05-07 CN claimed
CN-115368331-B Dihydro-pyrone compound and preparation method and application thereof 复旦大学 2024-04-30 CN claimed
CN-115368332-B Synthesis method and application of 6-aryl/alkylthio-2H-pyran-3-ketone compound 三峡大学 2024-03-12 CN claimed
CN-117510448-A Dihydropyrone derivative and preparation method and application thereof 贵州中医药大学 2024-02-06 CN claimed
WO-2023195791-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT 케이블루바이오 주식회사 2023-10-12 WO claimed
US-20230322765-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US claimed
EP-4172158-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH The Regents of the University of California (US) 2023-05-03 EP claimed
WO-1993006236-A1 ENZYMATIC PRODUCTION OF OPTICAL ISOMERS OF TETRAHYDROPYRAN-2-ONES ZENECA LIMITED (GB) 1993-04-01 WO claimed
WO-1993006235-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES ZENECA LIMITED (GB) 1993-04-01 WO claimed
EP-0401505-A2 Pharmaceutical composition containing a potassium channel-activator and an ace-inhibitor MERCK PATENT GmbH (DE) 1990-12-12 EP claimed
EP-0285936-B1 3,4-DIHYDRO-2H-PYRANS BASF Aktiengesellschaft (DE) 1990-05-30 EP claimed
EP-0228546-B1 METHOD FOR THE PREPARATION OF 4'-0-TETRAHYDROPYRANYLADRIAMYCIN B Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) 1989-09-13 EP claimed
EP-0131232-B1 STEREOSELECTIVE PROCESS FOR THE PREPARATION OF ANTHRACYCLINE DERIVATIVES MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1987-12-23 EP claimed
EP-0081090-B1 PROCESS FOR THE PREPARATION OF 3,4-DIHYDRO-ALPHA-PYRONES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1987-08-05 EP claimed
US-4673751-A Method of preparing 3,4-dihydro-alpha-pyrones DYNAMIT NOBEL AG (DE) 1987-06-16 US claimed
EP-0075680-B1 SUBSTITUTED FURANONES AND PROCESS FOR PREPARING 3,4-DIHYDRO-ALPHA-PYRONES AND SUBSTITUTED FURANONES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1986-11-20 EP claimed
EP-0131779-A1 Method for the preparation of 3,4-dihydro-alpha pyrones HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1985-01-23 EP claimed