Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24736516 | 1.00 | LMNA (0.52) | LMNAPOLBNTRK1STING1GAA | |
| Penthiopyrad SCHEMBL14364841 | 0.91 | LMNA (0.51) | LMNAPOLBNTRK1STING1GAA | |
| Penthiopyrad SCHEMBL14364842 | 0.91 | LMNA (0.51) | LMNAPOLBNTRK1STING1GAA | |
| Penthiopyrad SCHEMBL18701 | 0.91 | LMNA (0.51) | LMNAPOLBNTRK1STING1GAA | |
| SCHEMBL7457962 | 0.90 | LMNA (0.55) | LMNAPOLBNTRK1STING1GAA | |
| SCHEMBL3115318 | 0.90 | LMNA (0.50) | LMNAPOLBNTRK1STING1GAA | |
| Penthiopyrad SCHEMBL22556056 | 0.88 | LMNA (0.51) | LMNAPOLBNTRK1STING1GAA | |
| Penthiopyrad SCHEMBL22556057 | 0.86 | LMNA (0.47) | LMNAPOLBNTRK1STING1GAA | |
| SCHEMBL6128085 | 0.86 | LMNA (0.47) | LMNAPOLBNTRK1STING1GAA | |
| SCHEMBL5634323 | 0.85 | LMNA (0.49) | LMNAPOLBNTRK1STING1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737682-B1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI CHEMICALS INC (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5747518-A | EFFECTIVE AGAINST CHEMICAL RESISTANT FUNGI; NONPHYTOTOXIC TO CROPS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0737682-A1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-10-16 | — | — | EP | disclosed |