Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | KHK | P50053 | 6/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465375 | 1.00 | F10 (0.38) | F10F2KHKITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7476507 | 0.89 | KHK (0.36) | F10F2KHKCYP17A1HRH3 | |
| SCHEMBL7466178 | 0.89 | KHK (0.43) | F10F2KHKITGB3ITGA2B | |
| SCHEMBL7466183 | 0.89 | KHK (0.43) | F10F2KHKITGB3ITGA2B | |
| SCHEMBL8561618 | 0.83 | F2 (0.39) | F10F2KHKITGB3ITGA2B | |
| SCHEMBL8562349 | 0.83 | F2 (0.39) | F10F2KHKCYP17A1HRH3 | |
| SCHEMBL8562341 | 0.83 | F2 (0.39) | F10F2KHKCYP17A1HRH3 | |
| SCHEMBL8561622 | 0.83 | F2 (0.39) | F10F2KHKITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8567119 | 0.82 | F2 (0.38) | F10F2KHKITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8560749 | 0.82 | F2 (0.38) | F10F2KHKCYP17A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | claimed |
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |