Urea

Urea

SCHEMBL7465407

CC=CCCC.NC(N)=O

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.45
SOAT1 P35610 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
KMT2A Q03164 1/20 0.45
CNR1 P21554 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TERT O14746 2/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL28235667 0.92 FAAH (0.43) FAAHSOAT1CYP1A2CYP2C19MEN1
Bicarbonate SCHEMBL702752 0.86 PPARG (0.41) FAAHCYP1A2CYP2C19KMT2ATERT
Bicarbonate SCHEMBL16774505 0.86 PPARG (0.41) FAAHCYP1A2CYP2C19KMT2ATERT
Acetic Acid SCHEMBL28194384 0.84 FAAH (0.38) FAAHSOAT1CYP1A2CYP2C19MEN1
Acetic Acid SCHEMBL28235496 0.84 PPARG (0.40) FAAHCYP1A2CYP2C19KMT2ATERT
Acetic Acid SCHEMBL29108691 0.84 PPARG (0.40) FAAHCYP1A2CYP2C19KMT2ATERT
SCHEMBL119259 0.83
SCHEMBL19007 0.83
SCHEMBL30099 0.83
Urea SCHEMBL29070646 0.81 FAAH (0.70) FAAHSOAT1CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810996-B1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIQIANG ALEX (US) 2002-10-09 EP claimed
EP-0810996-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS He, Zhiqiang Alex (US) 1997-12-10 EP claimed
WO-1996026189-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIGIANG ALEX (US) 1996-08-29 WO claimed
EP-0810996-B1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIQIANG ALEX (US) 2002-10-09 EP disclosed