Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | DRD4 | P21917 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696807 | 0.88 | KMT2A (0.57) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL11050996 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1GAAPOLBMAPK1 | |
| SCHEMBL12177908 | 0.83 | CYP1A2 (0.63) | KDM4EALDH1A1GAAKMT2AMAPK1 | |
| SCHEMBL10650029 | 0.83 | CYP2D6 (0.67) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL17303741 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL5251060 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1GAAPOLBMAPK1 | |
| SCHEMBL59488 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL15295402 | 0.81 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL10287572 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL8349049 | 0.80 | TSHR (0.65) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |