SCHEMBL7465893

SCHEMBL7465893

COC(=O)CNc1ccc(S(N)(=O)=O)c(C(=O)OC)c1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.52
CA1 P00915 10/20 0.52
CA9 Q16790 9/20 0.52
CA5A P35218 1/20 0.52
CDK1 P06493 1/20 0.50
CA12 O43570 9/20 0.47
CA14 Q9ULX7 3/20 0.47
EGFR P00533 5/20 0.43
NOX4 Q9NPH5 1/20 0.43
CA7 P43166 1/20 0.41
TOP2A P11388 1/20 0.39
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662947 0.78 CA2 (0.52) CA2CA1CA9CA5ACDK1
SCHEMBL11226378 0.75 CA2 (0.63) CA2CA1CA9CA5ACDK1
SCHEMBL21962910 0.75 CA2 (0.63) CA2CA1CA9CA5ACDK1
SCHEMBL30827404 0.75 CA2 (0.63) CA2CA1CA9CA5ACDK1
SCHEMBL9724848 0.74 CA2 (0.58) CA2CA1CA9CA5ACDK1
SCHEMBL7465436 0.74 CDK1 (0.42) CDK1ALDH1A1
SCHEMBL21962963 0.74 CA2 (0.54) CA2CA1CA9CA5ACDK1
SCHEMBL22827959 0.74 CA2 (0.61) CA2CA1CA9CA5ACDK1
SCHEMBL9143218 0.74 CA2 (0.61) CA2CA1CA9CA5ACDK1
SCHEMBL22827732 0.74 CA2 (0.61) CA2CA1CA9CA5ACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0706518-B1 ACYLATED AMINOPHENYL UREA COMPOUNDS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS AVENTIS CROPSCIENCE GMBH (DE) 2002-01-02 EP disclosed
US-5658854-A Acylated aminophenylsulfonylureas; preparation and use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1997-08-19 US disclosed
EP-0706518-A1 ACYLATED AMINOPHENYL UREA COMPOUNDS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1996-04-17 EP disclosed
WO-1995001344-A1 ACYLATED AMINOPHENYL UREA COMPOUNDS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-01-12 WO disclosed