Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 11/20 | 0.58 |
| ▸ | CCR3 | P51677 | 7/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462401 | 0.91 | CCR5 (0.60) | CCR5CCR3HTR2AOPRM1 | |
| Hydrochloric Acid SCHEMBL7465772 | 0.88 | CCR5 (0.70) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7453166 | 0.88 | CCR5 (0.60) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7462330 | 0.88 | CCR5 (0.62) | CCR5 | |
| Hydrochloric Acid SCHEMBL7463930 | 0.88 | CCR5 (0.60) | CCR5OPRM1 | |
| SCHEMBL3038736 | 0.85 | CCR5 (0.62) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7468720 | 0.85 | CCR5 (0.57) | CCR5CCR3OPRM1 | |
| Hydrochloric Acid SCHEMBL7464275 | 0.85 | CCR5 (0.62) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7460754 | 0.84 | CCR5 (0.56) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7463675 | 0.84 | CCR5 (0.57) | CCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |