Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978870 | 0.82 | TDP1 (0.45) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL18371959 | 0.74 | POLB (0.46) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL7472335 | 0.74 | POLB (0.46) | ALDH1A1TDP1TSHRPOLBTP53 | |
| SCHEMBL7472535 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TDP1TSHRPOLBHPGD | |
| SCHEMBL1616513 | 0.70 | ALDH1A1 (0.69) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL7472383 | 0.70 | POLB (0.45) | ALDH1A1TDP1POLBSMN1; SMN2KDM4E | |
| SCHEMBL7473306 | 0.70 | POLB (0.45) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL7479289 | 0.70 | POLB (0.45) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL4495805 | 0.70 | POLB (0.46) | ALDH1A1TDP1POLBSMN1; SMN2 | |
| SCHEMBL17049183 | 0.69 | POLB (0.46) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |