Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.88 |
| ▸ | HTR1D | P28221 | 6/20 | 0.88 |
| ▸ | HTR1B | P28222 | 6/20 | 0.88 |
| ▸ | HTR1A | P08908 | 5/20 | 0.88 |
| ▸ | HTR2A | P28223 | 2/20 | 0.88 |
| ▸ | HTR7 | P34969 | 2/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947189 | 0.89 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3949519 | 0.87 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3947299 | 0.87 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3946584 | 0.83 | HTR6 (0.72) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL1776854 | 0.82 | HTR6 (0.64) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL1776286 | 0.81 | HTR6 (0.63) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL6829584 | 0.81 | HTR6 (0.65) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3948620 | 0.79 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3617129 | 0.77 | HTR6 (0.64) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3952668 | 0.77 | HTR6 (0.63) | HTR6HTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |