Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 16/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 16/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.46 |
| ▸ | GCG | P01275 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | COASY | Q13057 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951658 | 0.78 | NPC1 (0.38) | ADRB1ADRB3ADRB2ALDH1A1HPGD | |
| SCHEMBL12951574 | 0.78 | NPC1 (0.38) | ADRB1ADRB3ADRB2ALDH1A1HPGD | |
| SCHEMBL12951577 | 0.78 | NPC1 (0.38) | ADRB1ADRB3ADRB2ALDH1A1HPGD | |
| SCHEMBL745384 | 0.77 | AKR1C3 (0.43) | — | |
| SCHEMBL140819 | 0.77 | GCGR (0.58) | ALDH1A1 | |
| SCHEMBL12951572 | 0.76 | TRPV1 (0.43) | ADRB1ADRB3ADRB2ALDH1A1HPGD | |
| SCHEMBL12951578 | 0.76 | HPGD (0.37) | ADRB1ADRB3ADRB2ALDH1A1HPGD | |
| SCHEMBL244322 | 0.74 | GPR35 (0.43) | — | |
| SCHEMBL178522 | 0.69 | GCG (0.40) | GCGALDH1A1 | |
| SCHEMBL27605316 | 0.68 | KMT2A (0.44) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431362-A1 | 3-(4-AMINOPHENYL)-2-FURANCARBOXYLIC ACID DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-03-21 | — | — | EP | disclosed |