Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461347 | 0.87 | GAA (0.54) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7465541 | 0.86 | GAA (0.53) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9741294 | 0.86 | GAA (0.48) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7466638 | 0.82 | NR4A2 (0.53) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7531657 | 0.82 | NR4A2 (0.59) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL1591706 | 0.81 | POLB (0.58) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7466122 | 0.80 | KMT2A (0.65) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9446960 | 0.78 | GAA (0.64) | GAAHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL12154377 | 0.77 | MEN1 (0.57) | GAAALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9266291 | 0.77 | HPGD (1.00) | GAAHPGDALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |