Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531657 | 0.93 | NR4A2 (0.59) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7458487 | 0.88 | NR4A2 (0.41) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7461220 | 0.88 | NR4A2 (0.47) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7471877 | 0.88 | NR4A2 (0.47) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7465295 | 0.88 | KDM4E (0.58) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7464015 | 0.88 | NR4A2 (0.47) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7464651 | 0.88 | NR4A2 (0.47) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7464982 | 0.85 | L3MBTL1 (0.46) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7044612 | 0.85 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7458613 | 0.85 | NR4A2 (0.54) | NR4A2KDM4EALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1031263-C | Quinoline, quinazoline, and cinnoline | LILLY CO ELI (US) | 1996-03-13 | — | — | CN | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |