Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460900 | 0.84 | CMA1 (0.58) | CMA1MCL1KMT2ATDP1CA9 | |
| SCHEMBL7465314 | 0.82 | CMA1 (0.71) | CMA1MCL1KMT2ACA9CA12 | |
| SCHEMBL7467052 | 0.78 | CMA1 (0.79) | CMA1KMT2ACA9MAPTKDM4E | |
| SCHEMBL3783551 | 0.77 | CMA1 (0.69) | CMA1CA9KDM4ECA12 | |
| SCHEMBL7465666 | 0.77 | CMA1 (0.85) | CMA1CA9CA12 | |
| SCHEMBL7463672 | 0.77 | CMA1 (1.00) | CMA1CA9CA12 | |
| SCHEMBL7458004 | 0.76 | CMA1 (0.61) | CMA1CA9KDM4ECA12 | |
| SCHEMBL7468062 | 0.75 | CMA1 (0.77) | CMA1L3MBTL1CA9MAPTKDM4E | |
| SCHEMBL3788201 | 0.75 | CMA1 (0.85) | CMA1CA9CA12 | |
| SCHEMBL7462562 | 0.75 | CMA1 (0.72) | CMA1KMT2ACA9MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |