Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 15/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | WNT3 | P56703 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053630 | 0.91 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL7465113 | 0.89 | ITGB3 (0.45) | ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL7470398 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7048411 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7469429 | 0.86 | ITGB3 (0.43) | ITGB3ITGAVITGA2BSFRP1 | |
| SCHEMBL7474930 | 0.86 | ITGB3 (0.43) | ITGB3ITGAVITGA2BSFRP1 | |
| SCHEMBL7462239 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL7468383 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL7462037 | 0.84 | ITGB3 (0.64) | ITGB3ITGAVITGA2B | |
| SCHEMBL382702 | 0.82 | ITGB3 (0.46) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |