Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 13/20 | 0.39 |
| ▸ | OXTR | P30559 | 3/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8742785 | 0.99 | AVPR1B (0.39) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| Water SCHEMBL8589898 | 0.99 | AVPR1B (0.39) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL7468172 | 0.91 | AVPR1B (0.43) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL3230001 | 0.91 | AVPR1A (0.39) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL7470867 | 0.90 | AVPR1B (0.40) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL7472393 | 0.88 | KMT2A (0.42) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7476157 | 0.88 | AVPR1A (0.38) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL7471393 | 0.85 | AVPR1B (0.49) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL3272128 | 0.81 | AVPR1A (0.41) | AVPR1AAVPR1BOXTRAVPR2GPR65 | |
| SCHEMBL3229249 | 0.81 | AVPR1A (0.41) | AVPR1AOXTRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |