Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230001 | 0.88 | AVPR1A (0.39) | AVPR1AOXTRMAPTSMN1; SMN2LMNA | |
| SCHEMBL3235049 | 0.85 | OXTR (0.53) | AVPR1AOXTRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3272128 | 0.81 | AVPR1A (0.41) | AVPR1AOXTRMAPTTHRBSMN1; SMN2 | |
| SCHEMBL7466977 | 0.81 | AVPR1A (0.39) | AVPR1AOXTRMAPTSMN1; SMN2LMNA | |
| SCHEMBL7470867 | 0.81 | AVPR1B (0.40) | AVPR1AOXTRMAPTSMN1; SMN2LMNA | |
| Water SCHEMBL8742785 | 0.80 | AVPR1B (0.39) | AVPR1AOXTRMAPTSMN1; SMN2LMNA | |
| Water SCHEMBL8589898 | 0.80 | AVPR1B (0.39) | AVPR1AOXTRMAPTSMN1; SMN2LMNA | |
| SCHEMBL3233606 | 0.80 | AVPR1A (0.55) | AVPR1AOXTRL3MBTL1GNRHRMAPT | |
| SCHEMBL7476157 | 0.79 | AVPR1A (0.38) | AVPR1AOXTRMAPTTHRBSMN1; SMN2 | |
| SCHEMBL3237129 | 0.79 | AVPR1A (0.51) | AVPR1AOXTRL3MBTL1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097374-B1 | 5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY AS SELECTIVE LIGANDS OF V2 VASOPRESSIN RECEPTORS | SANOFI AVENTIS (FR) | 2010-06-09 | — | — | EP | disclosed |
| US-20100069384-A1 | 5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069384-A1 | 5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY | AVPR2, AVPR1A, AVPR1B | AVPR1A 2/4885OXTR 6/4885L3MBTL1 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.