Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468346 | 0.85 | SMN1; SMN2 (0.43) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7463262 | 0.77 | GSK3B (0.32) | CSNK2A1CSNK2BADORA3ADORA2AADORA1 | |
| SCHEMBL7469470 | 0.73 | DPYD (0.40) | KDM4EKDM6BHPGD | |
| SCHEMBL27409257 | 0.71 | KDM3B (0.41) | KDM4EKDM3BCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL1554484 | 0.69 | PDE4A (0.53) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL828410 | 0.67 | PARP1 (0.61) | KDM4EHPGD | |
| SCHEMBL13295349 | 0.65 | KDM6B (0.56) | KDM4EKDM3BKDM6BKDM4AKDM4D | |
| SCHEMBL22487726 | 0.64 | SLC2A1 (0.58) | SLC2A1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7443209 | 0.64 | KDM4E (0.40) | KDM4ESLC2A1HPGDHSD17B10ADORA3 | |
| SCHEMBL15469076 | 0.63 | DYRK1A (0.55) | KDM4EKDM3BDYRK1ANOTUMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117664-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GmbH (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020416-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2000-04-13 | — | — | WO | disclosed |