Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465663 | 0.90 | MCHR1 (0.75) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7470308 | 0.89 | MCHR1 (0.70) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7467049 | 0.87 | MCHR1 (0.73) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7459157 | 0.86 | MCHR1 (0.67) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7461152 | 0.86 | MCHR1 (0.64) | MCHR1SIGMAR1KMT2AHTR7 | |
| SCHEMBL7467035 | 0.84 | MCHR1 (0.62) | MCHR1SIGMAR1HTR7 | |
| SCHEMBL7460592 | 0.84 | MCHR1 (0.62) | MCHR1SIGMAR1HTR7CCR1CCR3 | |
| SCHEMBL7462251 | 0.84 | MCHR1 (0.82) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7460174 | 0.84 | MCHR1 (0.59) | MCHR1SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7465506 | 0.83 | MCHR1 (0.84) | MCHR1SIGMAR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |