SCHEMBL7467337

SCHEMBL7467337

CC(C)CC(C(=O)O)[C@H](CCC(F)(F)F)NOC1CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7377470 1.00 MEN1 (0.31) MEN1KMT2A
SCHEMBL7410645 0.89 MEN1 (0.32) MEN1KMT2A
SCHEMBL7380889 0.89 MEN1 (0.32) MEN1KMT2A
SCHEMBL7380103 0.89 MEN1 (0.32) MEN1KMT2A
SCHEMBL7382361 0.86 MEN1 (0.33) MEN1KMT2A
SCHEMBL7386458 0.86 MEN1 (0.33) MEN1KMT2A
SCHEMBL7383746 0.82 MEN1 (0.35) MEN1KMT2A
SCHEMBL7384882 0.80 MEN1 (0.34) MEN1KMT2A
SCHEMBL7474074 0.80 MEN1 (0.34) MEN1KMT2A
SCHEMBL7472659 0.80 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1019386-A1 REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2000-07-19 EP disclosed
WO-1998038179-A1 REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 1998-09-03 WO disclosed