Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384882 | 1.00 | MEN1 (0.34) | MEN1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL7383746 | 0.87 | MEN1 (0.35) | MEN1KMT2AMMP1MMP8ADAM17 | |
| SCHEMBL7386458 | 0.84 | MEN1 (0.33) | MEN1KMT2ASLC6A3CPA1 | |
| SCHEMBL7382361 | 0.84 | MEN1 (0.33) | MEN1KMT2ASLC6A3CPA1 | |
| SCHEMBL7380103 | 0.82 | MEN1 (0.32) | MEN1KMT2AHPGDTSHRMMP1 | |
| SCHEMBL7380889 | 0.82 | MEN1 (0.32) | MEN1KMT2AHPGDTSHRMMP1 | |
| SCHEMBL7410645 | 0.82 | MEN1 (0.32) | MEN1KMT2AHPGDTSHRMMP1 | |
| SCHEMBL7377470 | 0.80 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7467337 | 0.80 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7383043 | 0.75 | MMP1 (0.34) | HPGDTSHRNPSR1MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019386-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998038179-A1 | REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |