Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843464 | 0.76 | OPRL1 (0.60) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL7230071 | 0.74 | OPRL1 (0.45) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL13229259 | 0.73 | OPRM1 (0.51) | MEN1KMT2A | |
| SCHEMBL7468364 | 0.73 | OPRL1 (0.41) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL4441268 | 0.73 | SLC6A2 (0.43) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL23208259 | 0.72 | OPRL1 (0.37) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL7228658 | 0.71 | OPRL1 (0.42) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL7230273 | 0.70 | OPRL1 (0.44) | OPRL1CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL2987797 | 0.70 | SLC6A2 (0.37) | OPRL1CHRM3SLC6A3SLC6A4CHRM2 | |
| SCHEMBL4092897 | 0.70 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942909-B1 | BICYCLIC AMINE DERIVATIVES | SYNGENTA LTD (GB) | 2002-06-12 | — | — | EP | disclosed |