Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.68 |
| ▸ | PPARD | Q03181 | 11/20 | 0.61 |
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470854 | 1.00 | PPARA (0.68) | PPARAPPARDPPARG | |
| SCHEMBL6583679 | 0.95 | PPARA (0.65) | PPARAPPARDPPARG | |
| SCHEMBL6582264 | 0.92 | PPARA (0.79) | PPARAPPARDPPARG | |
| SCHEMBL6582575 | 0.91 | PPARA (0.63) | PPARAPPARDPPARG | |
| SCHEMBL6582860 | 0.88 | PPARA (0.77) | PPARAPPARDPPARG | |
| SCHEMBL7560728 | 0.81 | PPARA (0.64) | PPARAPPARDPPARG | |
| SCHEMBL5185069 | 0.79 | PPARA (0.82) | PPARAPPARDPPARG | |
| SCHEMBL6583647 | 0.79 | PPARA (0.80) | PPARAPPARDPPARG | |
| Gw590735 SCHEMBL3673228 | 0.77 | PPARA (1.00) | PPARAPPARDPPARG | |
| SCHEMBL6582584 | 0.75 | PPARA (1.00) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244642-A1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2002-10-02 | — | — | EP | claimed |
| WO-2001040207-A1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2001-06-07 | — | — | WO | claimed |