Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402068 | 0.95 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL4514092 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7475357 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7474110 | 0.84 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7468235 | 0.84 | ELANE (0.52) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7472745 | 0.83 | POLB (0.53) | SMN1; SMN2NPC1RAB9AMAPTCA12 | |
| SCHEMBL7475311 | 0.82 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL27420028 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7467896 | 0.81 | ELANE (0.54) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL7472353 | 0.81 | KDM4E (0.56) | SMN1; SMN2NPC1RAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |