Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459413 | 0.91 | CES2 (0.62) | ELANECES2CES1SMN1; SMN2TP53 | |
| SCHEMBL7471955 | 0.86 | RAB9A (0.49) | ELANESMN1; SMN2NPC1RAB9AMAPT | |
| Methyl 3-Methoxybenzoate SCHEMBL7469145 | 0.85 | SMN1; SMN2 (0.62) | ELANECES2CES1SMN1; SMN2TP53 | |
| SCHEMBL7471424 | 0.85 | HDAC8 (0.52) | ELANESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7475357 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2PARP1NPC1RAB9AMAPT | |
| SCHEMBL7468235 | 0.82 | ELANE (0.52) | ELANESMN1; SMN2PARP1NPC1RAB9A | |
| SCHEMBL7467749 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2PARP1NPC1RAB9AMAPT | |
| SCHEMBL7475311 | 0.81 | NPC1 (0.49) | CES2CES1SMN1; SMN2PARP1ESR1 | |
| SCHEMBL27420028 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2PARP1NPC1RAB9AMAPT | |
| SCHEMBL27427424 | 0.81 | HDAC8 (0.53) | SMN1; SMN2NPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |