SCHEMBL7467880

SCHEMBL7467880

Cc1cc(C)c(B(c2c(C)cc(C)cc2C)c2cccc3c(B(c4c(C)cc(C)cc4C)c4c(C)cc(C)cc4C)cccc23)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.42
CYP2A6 P11509 3/20 0.42
RAPGEF4 Q8WZA2 10/20 0.36
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACHE P22303 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7467805 0.92 CYP2A6 (0.47) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL7914780 0.89 CYP2A6 (0.50) CYP1A2CYP2A6NPC1MAPTRAB9A
SCHEMBL27633239 0.83 CYP1A2 (0.48) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL7456742 0.83 CYP1A2 (0.33) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL7909069 0.81 CYP1A2 (0.39) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL7465364 0.79 CYP1A2 (0.40) CYP1A2CYP2A6FFAR4ALDH1A1HPGD
SCHEMBL20396010 0.79 CYP1A2 (0.45) CYP1A2CYP2A6NPC1MAPTRAB9A
SCHEMBL7148799 0.79 CYP1A2 (0.38) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL7467096 0.78 CYP1A2 (0.50) CYP1A2CYP2A6RAPGEF4NPC1MAPT
SCHEMBL18462944 0.78 RAPGEF4 (0.45) CYP1A2CYP2A6RAPGEF4ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775706-B1 Borates photoinitiators from polyboranes CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-1203999-A2 Photoinitiator comprising a borane and an electron donating compound Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
US-6057078-A PHOTOGRAPHY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
US-5807905-A POLYMERIZATION OF UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
EP-0775706-A2 Borates photoinitiators from polyboranes Ciba SC Holding AG (CH) 1997-05-28 EP disclosed