Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473284 | 0.82 | GPR3 (0.44) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL7473289 | 0.82 | GPR3 (0.44) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL4567100 | 0.76 | ESR1 (0.64) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL13940432 | 0.76 | ESR1 (0.64) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL8792619 | 0.74 | GPR3 (0.47) | GPR3MEN1KMT2AMAOA | |
| SCHEMBL22650231 | 0.72 | GPR3 (0.54) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL10216422 | 0.72 | GPR3 (0.54) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL4567101 | 0.72 | ESR1 (0.51) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL13019511 | 0.72 | ESR1 (0.51) | GPR3ESR1ESR2MEN1KMT2A | |
| SCHEMBL12901133 | 0.72 | CHAT (0.47) | GPR3ESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |