Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784852 | 0.90 | CMA1 (0.67) | CMA1CA9PDE4APDE4BPDE4C | |
| SCHEMBL3777373 | 0.87 | CMA1 (0.62) | CMA1CA9CA12ALDH1A1SMN1; SMN2 | |
| SCHEMBL4455009 | 0.86 | CMA1 (0.59) | CMA1CA9PDE4APDE4BPDE4C | |
| SCHEMBL7467052 | 0.86 | CMA1 (0.79) | CMA1CA9CA12KDM4EMEN1 | |
| SCHEMBL7460050 | 0.85 | CMA1 (0.69) | CMA1CA9CA12ALDH1A1SMN1; SMN2 | |
| SCHEMBL7463672 | 0.84 | CMA1 (1.00) | CMA1CA9CA12SMN1; SMN2TP53 | |
| SCHEMBL7461914 | 0.82 | CMA1 (0.77) | CMA1CA9CA12ALDH1A1SMN1; SMN2 | |
| SCHEMBL7465666 | 0.82 | CMA1 (0.85) | CMA1CA9CA12SMN1; SMN2TP53 | |
| SCHEMBL7467623 | 0.81 | CMA1 (0.75) | CMA1CA9CA12ALDH1A1KDM4E | |
| SCHEMBL7462562 | 0.80 | CMA1 (0.72) | CMA1CA9CA12ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |