Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461872 | 0.87 | TYMP (0.34) | DGAT2SCN7AKCNH2FNTAFNTB | |
| SCHEMBL7472579 | 0.87 | TYMP (0.32) | DGAT2SCN7AKCNH2FNTAFNTB | |
| SCHEMBL7460798 | 0.86 | DGAT2 (0.32) | DGAT2SCN7AKCNH2FNTAFNTB | |
| SCHEMBL7468317 | 0.84 | SCN7A (0.32) | DGAT2SCN7AKCNH2FNTAFNTB | |
| SCHEMBL7590277 | 0.81 | FNTA (0.45) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL6913123 | 0.73 | TRIM24 (0.35) | SCN7AKCNH2FNTAFNTBFASN | |
| Hydrochloric Acid SCHEMBL7747644 | 0.71 | FNTA (0.37) | DGAT2FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL7593701 | 0.69 | FNTA (0.43) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7657808 | 0.68 | FNTA (0.44) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7591019 | 0.68 | FNTA (0.43) | KCNH2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165013-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1165013-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |
| WO-2000051547-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |