SCHEMBL7468853

SCHEMBL7468853

CCNC(=O)N(C)c1ccc(COc2cc(F)cc(C3(OC)CCOCC3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7478747 0.93 ALOX5 (0.56) ALOX5
SCHEMBL7473386 0.91 ALOX5 (0.56) ALOX5
SCHEMBL7534448 0.91 ALOX5 (0.59) ALOX5
SCHEMBL7484790 0.91 ALOX5 (0.56) ALOX5
SCHEMBL7478505 0.91 ALOX5 (0.54) ALOX5
SCHEMBL7473106 0.91 ALOX5 (0.55) ALOX5
SCHEMBL7476166 0.91 ALOX5 (0.55) ALOX5
SCHEMBL7483933 0.91 ALOX5 (0.55) ALOX5
SCHEMBL7477198 0.91 ALOX5 (0.55) ALOX5
SCHEMBL7481473 0.91 ALOX5 (0.57) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250332-A1 INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION Abbott Laboratories (US) 2002-10-23 EP disclosed
WO-2001044223-A1 INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION ABBOTT LABORATORIES (US) 2001-06-21 WO disclosed