Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | HRAS | P01112 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468134 | 0.97 | MAPT (0.49) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7470426 | 0.92 | MAPT (0.49) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7463992 | 0.90 | MAPT (0.49) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7464777 | 0.90 | MAPT (0.49) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7463241 | 0.90 | MAPT (0.42) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7469692 | 0.89 | MAPT (0.48) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7463869 | 0.89 | MAPT (0.48) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7464254 | 0.89 | MAPT (0.47) | MAPTMEN1POLBKMT2AMMP2 | |
| SCHEMBL7460611 | 0.88 | CNR1 (0.39) | MAPTMEN1POLBKMT2AHRAS | |
| SCHEMBL7472023 | 0.88 | HRAS (0.51) | MAPTMEN1POLBKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0776891-B1 | Pyrrolylbenzimidazole derivatives | MITSUI CHEMICALS INC (JP) | 1999-02-10 | — | — | EP | disclosed |
| EP-0776891-A1 | Pyrrolylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-06-04 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |