Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463869 | 0.97 | MAPT (0.48) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7469008 | 0.92 | MAPT (0.50) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7468134 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7469692 | 0.88 | MAPT (0.48) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7463992 | 0.87 | MAPT (0.49) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7464777 | 0.87 | MAPT (0.49) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7463241 | 0.87 | MAPT (0.42) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7472000 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7470394 | 0.85 | MAPT (0.47) | MAPTMEN1KMT2APOLBMMP2 | |
| SCHEMBL7467253 | 0.85 | MAPT (0.46) | MAPTMEN1KMT2APOLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |