Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl 3-Methoxybenzoate SCHEMBL27476346 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53CES2CES1NPC1 | |
| Methyl 3-Methoxybenzoate SCHEMBL29702092 | 0.90 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53CES2CES1NPC1 | |
| Methyl 3-Methoxybenzoate SCHEMBL384913 | 0.90 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53CES2CES1NPC1 | |
| SCHEMBL7466621 | 0.85 | KMT2A (0.51) | SMN1; SMN2TP53NPC1RAB9AMEN1 | |
| SCHEMBL7475996 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2CES2CES1NPC1RAB9A | |
| SCHEMBL7467896 | 0.85 | ELANE (0.54) | SMN1; SMN2TP53CES2CES1NPC1 | |
| SCHEMBL7468439 | 0.85 | MRGPRX4 (0.55) | SMN1; SMN2TP53NPC1RAB9APOLB | |
| SCHEMBL7467547 | 0.83 | POLB (0.55) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL5558318 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53CES2CES1NPC1 | |
| SCHEMBL7464641 | 0.83 | KMT2A (0.61) | SMN1; SMN2CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |